PrimePCR™ SYBR® Green Assay: CASP10, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

Info:   Same primer pair as used in probe assay qHsaCIP0027098

List Price:    $179.00
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Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCID0009223
Assay Design:   Intron-spanning
Chromosome Location:   2:202047932-202050554question
Amplicon Length:   131
Splice Variants Targeted:   ENST00000286186 ENST00000272879 ENST00000374650 ENST00000346817 ENST00000313728 ENST00000448480 ENST00000360132

Gene Information

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits large and small that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7 and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq Apr 2011]

Gene Symbol:   CASP10
Gene Name:   caspase 10, apoptosis-related cysteine peptidase
Aliases:   ALPS2, FLICE2, MCH4
RefSeq:   NC_000002.11 NT_005403.17 NG_007497.1 NG_007265.1
Ensembl:   ENSG00000003400
Entrez:   843
Chromosome Mapping:   2q33-q34

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