PrimePCR™ SYBR® Green Assay: LIMS1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

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Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCED0001328
Assay Design:   Exonic
Chromosome Location:   2:109300341-109300519question
Amplicon Length:   149
Splice Variants Targeted:   ENST00000332345 ENST00000393310 ENST00000410093 ENST00000409441 ENST00000338045 ENST00000544547 ENST00000542845

Gene Information

The protein encoded by this gene is an adaptor protein which contains five LIM domains or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2 which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Jul 2010]

Gene Symbol:   LIMS1
Gene Name:   LIM and senescent cell antigen-like domains 1
Aliases:   PINCH, PINCH1
RefSeq:   NC_000002.11 NT_022171.15
Ensembl:   ENSG00000169756
Entrez:   3987
Chromosome Mapping:   2q12.3

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