PrimePCR™ SYBR® Green Assay: MTA1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

Info:   Recommended - best coverage

List Price:    $179.00
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Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCED0001336
Assay Design:   Exonic
Chromosome Location:   14:105936178-105936421question
Amplicon Length:   141
Splice Variants Targeted:   ENST00000331320 ENST00000406191 ENST00000405646 ENST00000434050 ENST00000426567 ENST00000494981 ENST00000414153 ENST00000435036

Gene Information

This gene encodes a protein that was identified in a screen for genes expressed in metastatic cells specifically mammary adenocarcinoma cell lines. Expression of this gene has been correlated with the metastatic potential of at least two types of carcinomas although it is also expressed in many normal tissues. The role it plays in metastasis is unclear. It was initially thought to be the 70kD component of a nucleosome remodeling deacetylase complex NuRD but it is more likely that this component is a different but very similar protein. These two proteins are so closely related though that they share the same types of domains. These domains include two DNA binding domains a dimerization domain and a domain commonly found in proteins that methylate DNA. The profile and activity of this gene product suggest that it is involved in regulating transcription and that this may be accomplished by chromatin remodeling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Feb 2011]

Gene Symbol:   MTA1
Gene Name:   metastasis associated 1
Aliases:   Not Available
RefSeq:   NC_000014.8 NT_026437.12
Ensembl:   ENSG00000182979
Entrez:   9112
Chromosome Mapping:   14q32.3

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