PrimePCR™ SYBR® Green Assay: MMP14, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

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PrimePCR™ PreAmp for SYBR® Green Assay: MMP14, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for SYBR® Green Assay: MMP14, Human
Reaction:     200 x 20 µl reactions desalted
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding primer assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCED0001628
Assay Design:   Exonic
Chromosome Location:   14:23311125-23311214question
Amplicon Length:   60
Splice Variants Targeted:   ENST00000311852 ENST00000548761

Gene Information

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes such as embryonic development reproduction and tissue remodeling as well as in disease processes such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However the protein encoded by this gene is a member of the membrane-type MMP (MT-MMP) subfamily; each member of this subfamily contains a potential transmembrane domain suggesting that these proteins are expressed at the cell surface rather than secreted. This protein activates MMP2 protein and this activity may be involved in tumor invasion. [provided by RefSeq Jul 2008]

Gene Symbol:   MMP14
Gene Name:   matrix metallopeptidase 14 (membrane-inserted)
Aliases:   MMP-X1, MT1-MMP, MTMMP1
RefSeq:   NC_000014.8 NT_026437.12
Ensembl:   ENSG00000157227
Entrez:   4323
Chromosome Mapping:   14q11-q12

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