PrimePCR™ SYBR® Green Assay: PRKCG, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

Info:   Recommended - best coverage; Same primer pair as used in probe assay qHsaCEP0051412

List Price:    $179.00
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Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCED0044150
Assay Design:   exonic
Chromosome Location:   19:54394976-54395767question
Amplicon Length:   84
Splice Variants Targeted:   ENST00000474397 ENST00000263431 ENST00000540413 ENST00000536044 ENST00000542049

Gene Information

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. This protein kinase is expressed solely in the brain and spinal cord and its localization is restricted to neurons. It has been demonstrated that several neuronal functions including long term potentiation (LTP) and long term depression (LTD) specifically require this kinase. Knockout studies in mice also suggest that this kinase may be involved in neuropathic pain development. Defects in this protein have been associated with neurodegenerative disorder spinocerebellar ataxia-14 (SCA14). [provided by RefSeq Jul 2008]

Gene Symbol:   PRKCG
Gene Name:   protein kinase C, gamma
Aliases:   MGC57564, PKC-gamma, PKCC, PKCG, SCA14
RefSeq:   NC_000019.9 NG_009114.1 NT_011109.16
Ensembl:   ENSG00000126583
Entrez:   5582
Chromosome Mapping:   19q13.4

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