PrimePCR™ SYBR® Green Assay: DDIT3, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

Info:   Recommended - best coverage; Same primer pair as used in probe assay qHsaCEP0058013

List Price:    $179.00
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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCED0056908
Assay Design:   exonic
Chromosome Location:   12:57910812-57910954question
Amplicon Length:   113
Splice Variants Targeted:   ENST00000547303 ENST00000551116 ENST00000346473 ENST00000552740 ENST00000547526

Gene Information

This gene encodes a member of the CCAAT/enhancer-binding protein (C/EBP) family of transcription factors. The protein functions as a dominant-negative inhibitor by forming heterodimers with other C/EBP members such as C/EBP and LAP (liver activator protein) and preventing their DNA binding activity. The protein is implicated in adipogenesis and erythropoiesis is activated by endoplasmic reticulum stress and promotes apoptosis. Fusion of this gene and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in myxoid liposarcomas or Ewing sarcoma. Multiple alternatively spliced transcript variants encoding two isoforms with different length have been identified. [provided by RefSeq Aug 2010]

Gene Symbol:   DDIT3
Gene Name:   DNA-damage-inducible transcript 3
Aliases:   CEBPZ, CHOP, CHOP-10, CHOP10, GADD153, MGC4154
RefSeq:   NC_000012.11 NT_029419.12 NG_027674.1
Ensembl:   ENSG00000175197
Entrez:   1649
Chromosome Mapping:   12q13.1-q13.2

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