PrimePCR™ SYBR® Green Assay: RB1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

Info:   Recommended - best coverage

List Price:    $179.00
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Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCID0007095
Assay Design:   Intron-spanning
Chromosome Location:   13:49050927-49054156question
Amplicon Length:   96
Splice Variants Targeted:   ENST00000542917 ENST00000267163

Gene Information

The protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB) bladder cancer and osteogenic sarcoma. [provided by RefSeq Jul 2008]

Gene Symbol:   RB1
Gene Name:   retinoblastoma 1
Aliases:   OSRC, RB, p105-Rb, pRb, pp110
RefSeq:   NG_012874.1 NC_000013.10 NG_009009.1 NT_024524.14
Ensembl:   ENSG00000139687
Entrez:   5925
Chromosome Mapping:   13q14.2

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