PrimePCR™ SYBR® Green Assay: G6PC, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

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Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCID0016027
Assay Design:   Intron-spanning
Chromosome Location:   17:41061349-41062998question
Amplicon Length:   124
Splice Variants Targeted:   ENST00000253801

Gene Information

Glucose-6-phosphatase (G6Pase) is a multi-subunit integral membrane protein of the endoplasmic reticulum that is composed of a catalytic subunit and transporters for G6P inorganic phosphate and glucose. This gene (G6PC) is one of the three glucose-6-phosphatase catalytic-subunit-encoding genes in human: G6PC G6PC2 and G6PC3. Glucose-6-phosphatase catalyzes the hydrolysis of D-glucose 6-phosphate to D-glucose and orthophosphate and is a key enzyme in glucose homeostasis functioning in gluconeogenesis and glycogenolysis. Mutations in this gene cause glycogen storage disease type I (GSD1). This disease also known as von Gierke disease is a metabolic disorder characterized by severe hypoglycemia associated with the accumulation of glycogen and fat in the liver and kidneys.[provided by RefSeq Feb 2011]

Gene Symbol:   G6PC
Gene Name:   glucose-6-phosphatase, catalytic subunit
Aliases:   G6PC1, G6PT, GSD1, GSD1a, MGC163350
RefSeq:   NC_000017.10 NG_011808.1 NT_010783.15
Ensembl:   ENSG00000131482
Entrez:   2538
Chromosome Mapping:   17q21

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