PrimePCR™ SYBR® Green Assay: SEPT5, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

Info:   Same primer pair as used in probe assay qHsaCEP0024649

List Price:    $179.00
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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCED0003279
Assay Design:   Exonic
Chromosome Location:   22:19708088-19708180question
Amplicon Length:   63
Splice Variants Targeted:   ENST00000455784 ENST00000406395 ENST00000412544 ENST00000431124 ENST00000383045 ENST00000438754 ENST00000395109 ENST00000446882

Gene Information

This gene is a member of the septin gene family of nucleotide binding proteins originally described in yeast as cell division cycle regulatory proteins. Septins are highly conserved in yeast Drosophila and mouse and appear to regulate cytoskeletal organization. Disruption of septin function disturbs cytokinesis and results in large multinucleate or polyploid cells. This gene is mapped to 22q11 the region frequently deleted in DiGeorge and velocardiofacial syndromes. A translocation involving the MLL gene and this gene has also been reported in patients with acute myeloid leukemia. Alternative splicing results in multiple transcript variants. The presence of a non-consensus polyA signal (AACAAT) in this gene also results in read-through transcription into the downstream neighboring gene (GP1BB; platelet glycoprotein Ib) whereby larger non-coding transcripts are produced. [provided by RefSeq Dec 2010]

Gene Symbol:   SEPT5
Gene Name:   septin 5
Aliases:   CDCREL, CDCREL-1, CDCREL1, H5, HCDCREL-1, PNUTL1
RefSeq:   NC_000022.10 NG_007974.1 NT_011519.10
Ensembl:   ENSG00000184702
Entrez:   5413
Chromosome Mapping:   22q11.21

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