PrimePCR™ SYBR® Green Assay: CTSL1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

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Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCID0010759
Assay Design:   Intron-spanning
Chromosome Location:   9:90344595-90345350question
Amplicon Length:   81
Splice Variants Targeted:   ENST00000343150 ENST00000340342

Gene Information

The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin as well as alpha-1 protease inhibitor a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes including myofibril necrosis in myopathies and in myocardial ischemia and in the renal tubular response to proteinuria. This protein which is a member of the peptidase C1 family is a dimer composed of disulfide-linked heavy and light chains both produced from a single protein precursor. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq Apr 2012]

Gene Symbol:   CTSL1
Gene Name:   cathepsin L1
Aliases:   CATL, CTSL, FLJ31037, MEP
RefSeq:   NC_000009.11 NT_008470.19
Ensembl:   ENSG00000135047
Entrez:   1514
Chromosome Mapping:   9q21.33

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