PrimePCR™ SYBR® Green Assay: PTGIS, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

Info:   Recommended - best efficiency

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Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCID0015120
Assay Design:   Intron-spanning
Chromosome Location:   20:48156206-48160882question
Amplicon Length:   64
Splice Variants Targeted:   ENST00000244043

Gene Information

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol steroids and other lipids. However this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2) a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction stroke and atherosclerosis. [provided by RefSeq Jul 2008]

Gene Symbol:   PTGIS
Gene Name:   prostaglandin I2 (prostacyclin) synthase
Aliases:   CYP8, CYP8A1, MGC126858, MGC126860, PGIS, PTGI
RefSeq:   NC_000020.10 NG_007940.1 NT_011362.10
Ensembl:   ENSG00000124212
Entrez:   5740
Chromosome Mapping:   20q13.13

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