PrimePCR™ SYBR® Green Assay: MSH6, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

Info:   Same primer pair as used in probe assay qHsaCEP0050925

List Price:    $179.00
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Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCED0043663
Assay Design:   exonic
Chromosome Location:   2:48018102-48018207question
Amplicon Length:   76
Splice Variants Targeted:   ENST00000234420 ENST00000455383 ENST00000420813 ENST00000411819 ENST00000538136

Gene Information

This gene encodes a protein similar to the MutS protein. In E. coli the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa called the Walker-A adenine nucleotide binding motif exists in MutS homologs. The encoded protein of this gene combines with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene have been identified in individuals with hereditary nonpolyposis colon cancer (HNPCC) and endometrial cancer. [provided by RefSeq Jul 2008]

Gene Symbol:   MSH6
Gene Name:   mutS homolog 6 (E. coli)
Aliases:   GTBP, HNPCC5, HSAP
RefSeq:   NC_000002.11 NG_007111.1 NG_008397.1 NT_022184.15
Ensembl:   ENSG00000116062
Entrez:   2956
Chromosome Mapping:   2p16

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