PrimePCR™ SYBR® Green Assay: NKX2-1, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

Info:   Same primer pair as used in probe assay qHsaCEP0058447

List Price:    $179.00
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Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qHsaCED0057342
Assay Design:   exonic
Chromosome Location:   14:36987030-36987176question
Amplicon Length:   117
Splice Variants Targeted:   ENST00000354822 ENST00000498187 ENST00000518149 ENST00000522719 ENST00000340308 ENST00000447932 ENST00000326232 ENST00000469193 ENST00000429996

Gene Information

This gene encodes a protein initially identified as a thyroid-specific transcription factor. The encoded protein binds to the thyroglobulin promoter and regulates the expression of thyroid-specific genes but has also been shown to regulate the expression of genes involved in morphogenesis. Mutations and deletions in this gene are associated with benign hereditary chorea choreoathetosis congenital hypothyroidism and neonatal respiratory distress and may be associated with thyroid cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares the symbol/alias 'TFF1' with another gene transcription termination factor 1 which plays a role in ribosomal gene transcription. [provided by RefSeq Apr 2011]

Gene Symbol:   NKX2-1
Gene Name:   NK2 homeobox 1
Aliases:   BCH, BHC, NK-2, NKX2.1, NKX2A, TEBP, TITF1, TTF-1, TTF1
RefSeq:   NC_000014.8 NG_013365.1 NT_026437.12
Ensembl:   ENSG00000136352
Entrez:   7080
Chromosome Mapping:   14q13

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