PrimePCR™ SYBR® Green Assay: Cldn11, Mouse

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

Info:   Same primer pair as used in probe assay qMmuCIP0036261

List Price:    $179.00
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PrimePCR™ PreAmp for SYBR® Green Assay: Cldn11, Mouse
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for SYBR® Green Assay: Cldn11, Mouse
Reaction:     200 x 20 µl reactions desalted
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding primer assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qMmuCID0024233
Assay Design:   Intron-spanning
Chromosome Location:   3:31154033-31163122question
Amplicon Length:   63
Splice Variants Targeted:   ENSMUST00000046174

Gene Information

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets and also play critical roles in maintaining cell polarity and signal transductions. The protein encoded by this gene is a major component of CNS (central nervous system) myelin and plays an important role in regulating proliferation and migration of oligodendrocytes. The basal cell tight junctions in stria vascularis are primarily composed of this protein and the gene-null mice suffer severe deafness. This protein is also an obligatory protein for tight junction formation and barrier integrity in the testis and the gene deficiency results in loss of the Sertoli cell epithelial phenotype in the testis. [provided by RefSeq Aug 2010]

Gene Symbol:   Cldn11
Gene Name:   Claudin 11
Aliases:   Claudin-11, Claudin11, Osp, Otm
RefSeq:   NC_000069.6 NT_162143.4
Ensembl:   ENSMUSG00000037625
Entrez:   18417
Chromosome Mapping:   3 A3|3 12.6 cM

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