PrimePCR™ SYBR® Green Assay: Cldn18, Mouse

PrimePCR Primer Assays for Real-Time PCR oligo primer pair tube for SYBR Green gene expression

Real-time PCR primer assay designed for SYBR® Green gene expression analysis.

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Assay Information

Technology:   qPCR
Assay Type:   SYBR® Green
Application:   Gene Expression
Unique Assay ID:   qMmuCID0025525
Assay Design:   Intron-spanning
Chromosome Location:   9:99696084-99698815question
Amplicon Length:   196
Splice Variants Targeted:   ENSMUST00000112882 ENSMUST00000131922 ENSMUST00000136429 ENSMUST00000035048

Gene Information

This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets and also play critical roles in maintaining cell polarity and signal transductions. This gene is a downstream target gene regulated by the T/EBP/NKX2.1 homeodomain transcription factor. Four alternatively spliced transcript variants resulted from alternative promoters and alternative splicing have been identified which encode two lung-specific isoforms and two stomach-specific isoforms respectively. This gene is also expressed in colons inner ear and skin and its expression is increased in both experimental colitis and ulcerative colitis. [provided by RefSeq Aug 2010]

Gene Symbol:   Cldn18
Gene Name:   Claudin 18
Aliases:   Not Available
RefSeq:   NC_000075.6 NT_039474.8
Ensembl:   ENSMUSG00000032473
Entrez:   56492
Chromosome Mapping:   9 E3-F1|9

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