PrimePCR™ Probe Assay: RANBP1, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

List Price:    $263.00
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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0024209
Assay Design:   Exonic
Chromosome Location:   22:20106536-20109795question
Amplicon Length:   115
Splice Variants Targeted:   ENST00000432879 ENST00000402752 ENST00000331821 ENST00000411892 ENST00000416427 ENST00000421656 ENST00000423859 ENST00000418705 ENST00000447917 ENST00000430524

Gene Information

Ran/TC4-binding protein RanBP1 interacts specifically with GTP-charged RAN. RANBP1 encodes a 23-kD protein that binds to RAN complexed with GTP but not GDP. RANBP1 does not activate GTPase activity of RAN but does markedly increase GTP hydrolysis by the RanGTPase-activating protein (RanGAP1). The RANBP1 cDNA encodes a 201-amino acid protein that is 92% similar to its mouse homolog. In both mammalian cells and in yeast RANBP1 acts as a negative regulator of RCC1 by inhibiting RCC1-stimulated guanine nucleotide release from RAN. [provided by RefSeq Jul 2008]

Gene Symbol:   RANBP1
Gene Name:   RAN binding protein 1
Aliases:   HTF9A, MGC88701
RefSeq:   NC_000022.10 NG_021420.1 NT_011519.10
Ensembl:   ENSG00000099901
Entrez:   5902
Chromosome Mapping:   22q11.21

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