PrimePCR™ Probe Assay: TNFSF4, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0039178
Assay Design:   exonic
Chromosome Location:   1:173153088-173153237question
Amplicon Length:   120
Splice Variants Targeted:   ENST00000367718 ENST00000281834

Gene Information

The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF4/OX4. It is found to be involved in T cell antigen-presenting cell (APC) interactions. In surface Ig- and CD40-stimulated B cells this cytokine along with CD70 has been shown to provide CD28-independent costimulatory signals to T cells. This protein and its receptor are reported to directly mediate adhesion of activated T cells to vascular endothelial cells. [provided by RefSeq Jul 2008]

Gene Symbol:   TNFSF4
Gene Name:   tumor necrosis factor (ligand) superfamily, member 4
Aliases:   CD134L, CD252, GP34, OX-40L, OX4OL, TXGP1
RefSeq:   NC_000001.10 NG_011477.1 NT_004487.19
Ensembl:   ENSG00000117586
Entrez:   7292
Chromosome Mapping:   1q25

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