PrimePCR™ Probe Assay: TRAF3IP2, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: TRAF3IP2, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: TRAF3IP2, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0049426
Assay Design:   exonic
Chromosome Location:   6:111880200-111880304question
Amplicon Length:   75
Splice Variants Targeted:   ENST00000368761 ENST00000359831 ENST00000340026 ENST00000368735 ENST00000392556

Gene Information

This gene encodes a protein involved in regulating responses to cytokines by members of the Rel/NF-kappaB transcription factor family. These factors play a central role in innate immunity in response to pathogens inflammatory signals and stress. This gene product interacts with TRAF proteins (tumor necrosis factor receptor-associated factors) and either I-kappaB kinase or MAP kinase to activate either NF-kappaB or Jun kinase. Several alternative transcripts encoding different isoforms have been identified. Another transcript which does not encode a protein and is transcribed in the opposite orientation has been identified. Overexpression of this transcript has been shown to reduce expression of at least one of the protein encoding transcripts suggesting it has a regulatory role in the expression of this gene. [provided by RefSeq Aug 2009]

Gene Symbol:   TRAF3IP2
Gene Name:   TRAF3 interacting protein 2
Aliases:   ACT1, C6orf2, C6orf4, C6orf5, C6orf6, CIKS, DKFZp586G0522, MGC3581
RefSeq:   NC_000006.11 NT_025741.15
Ensembl:   ENSG00000056972
Entrez:   10758
Chromosome Mapping:   6q21

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