PrimePCR™ Probe Assay: NFKB2, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: NFKB2, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: NFKB2, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0049657
Assay Design:   exonic
Chromosome Location:   10:104154513-104155734question
Amplicon Length:   79
Splice Variants Targeted:   ENST00000601386 ENST00000369966 ENST00000471698 ENST00000189444 ENST00000428099

Gene Information

This gene encodes one of the NF-kappaB family of transcription factors which are characterized by a Rel homology domain (RHD) in the N-terminal region. These transcription factors have key roles in regulating immunity stress responses apoptosis and differentiation. The p100 form of this gene is processed in the proteasome to the p52 form. NF-kappaB molecules containing p52 participate in noncanonical NF-kappaB regulatory pathways. Recent reviews of the NF-kappaB signalling pathways include PubMed 17072323 18267068 18515173 and 21772278. [provided by RefSeq Aug 2011]

Gene Symbol:   NFKB2
Gene Name:   nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100)
Aliases:   LYT-10, LYT10, p52
RefSeq:   NC_000010.10 NT_030059.13
Ensembl:   ENSG00000077150
Entrez:   4791
Chromosome Mapping:   10q24

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