PrimePCR™ Probe Assay: TRADD, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: TRADD, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: TRADD, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0050206
Assay Design:   exonic
Chromosome Location:   16:67188148-67188282question
Amplicon Length:   105
Splice Variants Targeted:   ENST00000345057 ENST00000486556

Gene Information

The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2 reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2 and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1 and is involved in the Fas-induced cell death pathway. [provided by RefSeq Jul 2008]

Gene Symbol:   TRADD
Gene Name:   TNFRSF1A-associated via death domain
Aliases:   Hs.89862, MGC11078
RefSeq:   NC_000016.9 NG_009294.1 NT_010498.15
Ensembl:   ENSG00000102871
Entrez:   8717
Chromosome Mapping:   16q22

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