PrimePCR™ Probe Assay: HEY2, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: HEY2, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: HEY2, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0051873
Assay Design:   exonic
Chromosome Location:   6:126081228-126081377question
Amplicon Length:   120
Splice Variants Targeted:   ENST00000368365 ENST00000368364

Gene Information

This gene encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcription factors. The encoded protein forms homo- or hetero-dimers that localize to the nucleus and interact with a histone deacetylase complex to repress transcription. Expression of this gene is induced by the Notch signal transduction pathway. Two similar and redundant genes in mouse are required for embryonic cardiovascular development and are also implicated in neurogenesis and somitogenesis. Alternatively spliced transcript variants have been found but their biological validity has not been determined. [provided by RefSeq Jul 2008]

Gene Symbol:   HEY2
Gene Name:   hairy/enhancer-of-split related with YRPW motif 2
Aliases:   CHF1, GRIDLOCK, GRL, HERP1, HESR2, HRT2, MGC10720, bHLHb32
RefSeq:   NC_000006.11 NT_025741.15
Ensembl:   ENSG00000135547
Entrez:   23493
Chromosome Mapping:   6q21

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