PrimePCR™ Probe Assay: ABCE1, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: ABCE1, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: ABCE1, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0053446
Assay Design:   exonic
Chromosome Location:   4:146049006-146049118question
Amplicon Length:   83
Splice Variants Targeted:   ENST00000296577

Gene Information

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1 MDR/TAP MRP ALD OABP GCN20 White). This protein is a member of the OABP subfamily. Alternatively referred to as the RNase L inhibitor this protein functions to block the activity of ribonuclease L. Activation of ribonuclease L leads to inhibition of protein synthesis in the 2-5A/RNase L system the central pathway for viral interferon action. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   ABCE1
Gene Name:   ATP-binding cassette, sub-family E (OABP), member 1
Aliases:   ABC38, OABP, RLI, RNASEL1, RNASELI, RNS4I
RefSeq:   NC_000004.11 NT_016354.19
Ensembl:   ENSG00000164163
Entrez:   6059
Chromosome Mapping:   4q31

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