PrimePCR™ Probe Assay: ANPEP, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

List Price:    $263.00
Your Price:   Log In
Quantity:  
 

PrimePCR™ PreAmp for Probe Assay: ANPEP, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: ANPEP, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0053669
Assay Design:   exonic
Chromosome Location:   15:90349677-90349823question
Amplicon Length:   117
Splice Variants Targeted:   ENST00000300060 ENST00000559874 ENST00000560137

Gene Information

Aminopeptidase N is located in the small-intestinal and renal microvillar membrane and also in other plasma membranes. In the small intestine aminopeptidase N plays a role in the final digestion of peptides generated from hydrolysis of proteins by gastric and pancreatic proteases. Its function in proximal tubular epithelial cells and other cell types is less clear. The large extracellular carboxyterminal domain contains a pentapeptide consensus sequence characteristic of members of the zinc-binding metalloproteinase superfamily. Sequence comparisons with known enzymes of this class showed that CD13 and aminopeptidase N are identical. The latter enzyme was thought to be involved in the metabolism of regulatory peptides by diverse cell types including small intestinal and renal tubular epithelial cells macrophages granulocytes and synaptic membranes from the CNS. Human aminopeptidase N is a receptor for one strain of human coronavirus that is an important cause of upper respiratory tract infections. Defects in this gene appear to be a cause of various types of leukemia or lymphoma. [provided by RefSeq Jul 2008]

Gene Symbol:   ANPEP
Gene Name:   alanyl (membrane) aminopeptidase
Aliases:   APN, CD13, GP150, LAP1, P150, PEPN
RefSeq:   NC_000015.9 NT_010274.17
Ensembl:   ENSG00000166825
Entrez:   290
Chromosome Mapping:   15q25-q26

[ Close ]
Click here to print
[ Close ]
Click here to print
 

undefined

undefined

My PrimePCR Hot List stores your saved PrimePCR products and configurations

My PrimePCR Hot List stores your saved PrimePCR products and configurations

undefined

undefined

undefined

undefined

undefined

undefined

undefined