PrimePCR™ Probe Assay: F2, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0054670
Assay Design:   exonic
Chromosome Location:   11:46748056-46748156question
Amplicon Length:   71
Splice Variants Targeted:   ENST00000442468 ENST00000530231 ENST00000311907

Gene Information

Coagulation factor II is proteolytically cleaved to form thrombin in the first step of the coagulation cascade which ultimately results in the stemming of blood loss. F2 also plays a role in maintaining vascular integrity during development and postnatal life. Mutations in F2 leads to various forms of thrombosis and dysprothrombinemia. [provided by RefSeq Jul 2008]

Gene Symbol:   F2
Gene Name:   coagulation factor II (thrombin)
Aliases:   PT
RefSeq:   NC_000011.9 NG_008953.1 NT_009237.18
Ensembl:   ENSG00000180210
Entrez:   2147
Chromosome Mapping:   11p11

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