PrimePCR™ Probe Assay: MMP9, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0028098
Assay Design:   Intron-spanning
Chromosome Location:   20:44641165-44641948question
Amplicon Length:   82
Splice Variants Targeted:   ENST00000372330 ENST00000545925

Gene Information

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes such as embryonic development reproduction and tissue remodeling as well as in disease processes such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The enzyme encoded by this gene degrades type IV and V collagens. Studies in rhesus monkeys suggest that the enzyme is involved in IL-8-induced mobilization of hematopoietic progenitor cells from bone marrow and murine studies suggest a role in tumor-associated tissue remodeling. [provided by RefSeq Jul 2008]

Gene Symbol:   MMP9
Gene Name:   matrix metallopeptidase 9 (gelatinase B, 92kDa gelatinase, 92kDa type IV collagenase)
Aliases:   CLG4B, GELB, MANDP2, MMP-9
RefSeq:   NC_000020.10 NG_011468.1 NT_011362.10
Ensembl:   ENSG00000100985
Entrez:   4318
Chromosome Mapping:   20q11.2-q13.1

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