PrimePCR™ Probe Assay: IL17A, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: IL17A, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: IL17A, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0030272
Assay Design:   Intron-spanning
Chromosome Location:   6:52052498-52053880question
Amplicon Length:   104
Splice Variants Targeted:   ENST00000340057

Gene Information

The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2) as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis psoriasis and multiple sclerosis. [provided by RefSeq Jul 2008]

Gene Symbol:   IL17A
Gene Name:   interleukin 17A
Aliases:   CTLA8, IL-17, IL-17A, IL17
RefSeq:   NC_000006.11 NT_007592.15
Ensembl:   ENSG00000112115
Entrez:   3605
Chromosome Mapping:   6p12

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