PrimePCR™ Probe Assay: PPIB, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: PPIB, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: PPIB, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0030902
Assay Design:   Intron-spanning
Chromosome Location:   15:64452327-64454347question
Amplicon Length:   148
Splice Variants Targeted:   ENST00000300026

Gene Information

The protein encoded by this gene is a cyclosporine-binding protein and is mainly located within the endoplasmic reticulum. It is associated with the secretory pathway and released in biological fluids. This protein can bind to cells derived from T- and B-lymphocytes and may regulate cyclosporine A-mediated immunosuppression. Variants have been identified in this protein that give rise to recessive forms of osteogenesis imperfecta. [provided by RefSeq Oct 2009]

Gene Symbol:   PPIB
Gene Name:   peptidylprolyl isomerase B (cyclophilin B)
Aliases:   CYP-S1, CYPB, MGC14109, MGC2224, OI9, SCYLP
RefSeq:   NC_000015.9 NG_012979.1 NT_010194.17
Ensembl:   ENSG00000166794
Entrez:   5479
Chromosome Mapping:   15q21-q22

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