PrimePCR™ Probe Assay: GSS, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: GSS, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: GSS, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0033248
Assay Design:   Intron-spanning
Chromosome Location:   20:33530742-33533836question
Amplicon Length:   119
Splice Variants Targeted:   ENST00000216951 ENST00000541098

Gene Information

Glutathione is important for a variety of biological functions including protection of cells from oxidative damage by free radicals detoxification of xenobiotics and membrane transport. The protein encoded by this gene functions as a homodimer to catalyze the second step of glutathione biosynthesis which is the ATP-dependent conversion of gamma-L-glutamyl-L-cysteine to glutathione. Defects in this gene are a cause of glutathione synthetase deficiency. [provided by RefSeq Jul 2008]

Gene Symbol:   GSS
Gene Name:   glutathione synthetase
Aliases:   GSHS, MGC14098
RefSeq:   NC_000020.10 NG_008848.1 NG_011520.1 NG_016984.1 NT_011362.10
Ensembl:   ENSG00000100983
Entrez:   2937
Chromosome Mapping:   20q11.2

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