PrimePCR™ Probe Assay: HDAC1, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: HDAC1, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: HDAC1, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0033252
Assay Design:   Intron-spanning
Chromosome Location:   1:32768261-32782316question
Amplicon Length:   95
Splice Variants Targeted:   ENST00000373548 ENST00000428704 ENST00000373541

Gene Information

Histone acetylation and deacetylation catalyzed by multisubunit complexes play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2 it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq Jul 2008]

Gene Symbol:   HDAC1
Gene Name:   histone deacetylase 1
Aliases:   DKFZp686H12203, GON-10, HD1, RPD3, RPD3L1
RefSeq:   NC_000001.10 NT_032977.9
Ensembl:   ENSG00000116478
Entrez:   3065
Chromosome Mapping:   1p34

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