PrimePCR™ Probe Assay: AREG, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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PrimePCR™ PreAmp for Probe Assay: AREG, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: AREG, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0039790
Assay Design:   Intron-spanning
Chromosome Location:   4:75312439-75314820question
Amplicon Length:   88
Splice Variants Targeted:   ENST00000395748 ENST00000502307 ENST00000264487 ENST00000380846

Gene Information

The protein encoded by this gene is a member of the epidermal growth factor family. It is an autocrine growth factor as well as a mitogen for astrocytes Schwann cells and fibroblasts. It is related to epidermal growth factor (EGF) and transforming growth factor alpha (TGF-alpha). This protein interacts with the EGF/TGF-alpha receptor to promote the growth of normal epithelial cells and inhibits the growth of certain aggressive carcinoma cell lines. This encoded protein is associated with a psoriasis-like skin phenotype. [provided by RefSeq Jul 2008]

Gene Symbol:   AREG
Gene Name:   amphiregulin
Aliases:   AR, AREGB, CRDGF, MGC13647, SDGF
RefSeq:   NC_000004.11 NT_022778.16
Ensembl:   ENSG00000109321
Entrez:   374
Chromosome Mapping:   4q13-q21

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