PrimePCR™ Probe Assay: AK2, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

List Price:    $263.00
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PrimePCR™ PreAmp for Probe Assay: AK2, Human
Reaction:     400 reactions
Gene-specific PCR primers for the unbiased preamplification of small quantities of cDNA for subsequent use in downstream gene expression analysis.

PrimePCR™ Template for Probe Assay: AK2, Human
Reaction:     200 x 20 µl reactions
Gene-specific synthetic DNA template designed to give a positive real-time PCR result when used with the corresponding probe assay.


Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0040639
Assay Design:   Intron-spanning
Chromosome Location:   1:33478959-33480189question
Amplicon Length:   82
Splice Variants Targeted:   ENST00000373449 ENST00000548033 ENST00000467905 ENST00000480134 ENST00000354858

Gene Information

Adenylate kinases are involved in regulating the adenine nucleotide composition within a cell by catalyzing the reversible transfer of phosphate groups among adenine nucleotides. Three isozymes of adenylate kinase namely 1 2 and 3 have been identified in vertebrates; this gene encodes isozyme 2. Expression of these isozymes is tissue-specific and developmentally regulated. Isozyme 2 is localized in the mitochondrial intermembrane space and may play a role in apoptosis. Mutations in this gene are the cause of reticular dysgenesis. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 1 and 2.[provided by RefSeq Nov 2010]

Gene Symbol:   AK2
Gene Name:   adenylate kinase 2
Aliases:   ADK2, AK 2
RefSeq:   NC_000001.10 NT_032977.9 NG_016269.1
Ensembl:   ENSG00000004455
Entrez:   204
Chromosome Mapping:   1p34

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