Gene:  F7, Human

PrimePCR Primer Assays for Real-Time PCR oligo primer pair gene expression assay target

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This gene encodes coagulation factor VII which is a vitamin K-dependent factor essential for hemostasis. This factor circulates in the blood in a zymogen form and is converted to an active form by either factor IXa factor Xa factor XIIa or thrombin by minor proteolysis. Upon activation of the factor VII a heavy chain containing a catalytic domain and a light chain containing 2 EGF-like domains are generated and two chains are held together by a disulfide bond. In the presence of factor III and calcium ions the activated factor then further activates the coagulation cascade by converting factor IX to factor IXa and/or factor X to factor Xa. Alternative splicing of this gene results in 2 transcripts. Defects in this gene can cause coagulopathy. [provided by RefSeq Jul 2008]

PrimePCR™ SYBR® Green Assay: F7, Rat
Coagulation factor VII Factor VII light chain Factor VII heavy chain

Assay Type: SYBR® Green
Assay Design: intron_spanning
Application: Gene Expression
Unique Assay ID: qRnoCID0007715
List Price:    $174.00
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PrimePCR™ Probe Assay: F7, Rat
Coagulation factor VII Factor VII light chain Factor VII heavy chain

Assay Type: Probe
Assay Design: intron_spanning
Application: Gene Expression
Unique Assay ID: qRnoCIP0029546
List Price:    $255.00
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