PrimePCR™ Probe Assay: PRF1, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

List Price:    $263.00
Your Price:   Log In
 

Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0039588
Assay Design:   exonic
Chromosome Location:   10:72357466-72357598question
Amplicon Length:   103
Splice Variants Targeted:   ENST00000373209 ENST00000441259

Gene Information

The protein encoded by this gene has structural and functional similarities to complement component 9 (C9). Like C9 this protein creates transmembrane tubules and is capable of lysing non-specifically a variety of target cells. This protein is one of the main cytolytic proteins of cytolytic granules and it is known to be a key effector molecule for T-cell- and natural killer-cell-mediated cytolysis. Defects in this gene cause familial hemophagocytic lymphohistiocytosis type 2 (HPLH2) a rare and lethal autosomal recessive disorder of early childhood. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq Jul 2008]

Gene Symbol:   PRF1
Gene Name:   perforin 1 (pore forming protein)
Aliases:   FLH2, HPLH2, MGC65093, P1, PFN1, PFP
RefSeq:   NC_000010.10 NG_009615.1 NT_030059.13
Ensembl:   ENSG00000180644
Entrez:   5551
Chromosome Mapping:   10q22

[ Close ]
Click here to print
[ Close ]
Click here to print
 

undefined

undefined

My PrimePCR Hot List stores your saved PrimePCR products and configurations

My PrimePCR Hot List stores your saved PrimePCR products and configurations

undefined

undefined

undefined

undefined

undefined

undefined

undefined