PrimePCR™ Probe Assay: NCOR1, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0040786
Assay Design:   exonic
Chromosome Location:   17:16097791-16097930question
Amplicon Length:   110
Splice Variants Targeted:   ENST00000395851 ENST00000268712 ENST00000395848 ENST00000411510 ENST00000582357 ENST00000436828 ENST00000430577

Gene Information

This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20.[provided by RefSeq Jun 2010]

Gene Symbol:   NCOR1
Gene Name:   nuclear receptor corepressor 1
Aliases:   KIAA1047, MGC104216, N-CoR, N-CoR1, TRAC1, hN-CoR
RefSeq:   NC_000017.10 NT_010718.16
Ensembl:   ENSG00000141027
Entrez:   9611
Chromosome Mapping:   17p11.2

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