PrimePCR™ Probe Assay: GCLM, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0049292
Assay Design:   exonic
Chromosome Location:   1:94354320-94354468question
Amplicon Length:   119
Splice Variants Targeted:   ENST00000370238

Gene Information

Glutamate-cysteine ligase also known as gamma-glutamylcysteine synthetase is the first rate limiting enzyme of glutathione synthesis. The enzyme consists of two subunits a heavy catalytic subunit and a light regulatory subunit. Gamma glutamylcysteine synthetase deficiency has been implicated in some forms of hemolytic anemia. [provided by RefSeq Jul 2008]

Gene Symbol:   GCLM
Gene Name:   glutamate-cysteine ligase, modifier subunit
Aliases:   GLCLR
RefSeq:   NC_000001.10 NG_012072.1 NT_032977.9
Ensembl:   ENSG00000023909
Entrez:   2730
Chromosome Mapping:   1p22.1

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