PrimePCR™ Probe Assay: CCL8, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0050502
Assay Design:   exonic
Chromosome Location:   17:32648202-32648312question
Amplicon Length:   81
Splice Variants Targeted:   ENST00000394620

Gene Information

This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes lymphocytes basophils and eosinophils. By recruiting leukocytes to sites of inflammation this cytokine may contribute to tumor-associated leukocyte infiltration and to the antiviral state against HIV infection. [provided by RefSeq Jul 2008]

Gene Symbol:   CCL8
Gene Name:   chemokine (C-C motif) ligand 8
Aliases:   HC14, MCP-2, MCP2, SCYA10, SCYA8
RefSeq:   NC_000017.10 NT_010799.15
Ensembl:   ENSG00000108700
Entrez:   6355
Chromosome Mapping:   17q11.2

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