PrimePCR™ Probe Assay: KAT2B, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0050799
Assay Design:   exonic
Chromosome Location:   3:20195594-20195711question
Amplicon Length:   88
Splice Variants Targeted:   ENST00000263754

Gene Information

CBP and p300 are large nuclear proteins that bind to many sequence-specific factors involved in cell growth and/or differentiation including c-jun and the adenoviral oncoprotein E1A. The protein encoded by this gene associates with p300/CBP. It has in vitro and in vivo binding activity with CBP and p300 and competes with E1A for binding sites in p300/CBP. It has histone acetyl transferase activity with core histones and nucleosome core particles indicating that this protein plays a direct role in transcriptional regulation. [provided by RefSeq Jul 2008]

Gene Symbol:   KAT2B
Gene Name:   K(lysine) acetyltransferase 2B
Aliases:   CAF, P, P/CAF, PCAF
RefSeq:   NC_000003.11 NT_022517.18
Ensembl:   ENSG00000114166
Entrez:   8850
Chromosome Mapping:   3p24

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