PrimePCR™ Probe Assay: DAD1, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0051536
Assay Design:   exonic
Chromosome Location:   14:23043984-23044127question
Amplicon Length:   114
Splice Variants Targeted:   ENST00000250498 ENST00000543337

Gene Information

DAD1 the defender against apoptotic cell death was initially identified as a negative regulator of programmed cell death in the temperature sensitive tsBN7 cell line. The DAD1 protein disappeared in temperature-sensitive cells following a shift to the nonpermissive temperature suggesting that loss of the DAD1 protein triggered apoptosis. DAD1 is believed to be a tightly associated subunit of oligosaccharyltransferase both in the intact membrane and in the purified enzyme thus reflecting the essential nature of N-linked glycosylation in eukaryotes. [provided by RefSeq Jul 2008]

Gene Symbol:   DAD1
Gene Name:   defender against cell death 1
Aliases:   OST2
RefSeq:   NC_000014.8 NT_026437.12
Ensembl:   ENSG00000129562
Entrez:   1603
Chromosome Mapping:   14q11.2

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