PrimePCR™ Probe Assay: ARPC1B, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0051575
Assay Design:   exonic
Chromosome Location:   7:98983399-98984409question
Amplicon Length:   75
Splice Variants Targeted:   ENST00000432884 ENST00000443222 ENST00000414376 ENST00000252725 ENST00000455009 ENST00000418347 ENST00000417330 ENST00000431816 ENST00000427217 ENST00000458033 ENST00000451682

Gene Information

This gene encodes one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1A. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages. This protein also has a role in centrosomal homeostasis by being an activator and substrate of the Aurora A kinase. [provided by RefSeq Mar 2011]

Gene Symbol:   ARPC1B
Gene Name:   actin related protein 2/3 complex, subunit 1B, 41kDa
Aliases:   ARC41, p40-ARC, p41-ARC
RefSeq:   NC_000007.13 NG_028040.1 NT_007933.15
Ensembl:   ENSG00000130429
Entrez:   10095
Chromosome Mapping:   7q22.1

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