PrimePCR™ Probe Assay: ANGPT1, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

List Price:    $263.00
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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0052887
Assay Design:   exonic
Chromosome Location:   8:108334189-108334332question
Amplicon Length:   114
Splice Variants Targeted:   ENST00000517746 ENST00000297450 ENST00000520734 ENST00000520052

Gene Information

Angiopoietins are proteins with important roles in vascular development and angiogenesis. All angiopoietins bind with similar affinity to an endothelial cell-specific tyrosine-protein kinase receptor. The protein encoded by this gene is a secreted glycoprotein that activates the receptor by inducing its tyrosine phosphorylation. It plays a critical role in mediating reciprocal interactions between the endothelium and surrounding matrix and mesenchyme and inhibits endothelial permeability. The protein also contributes to blood vessel maturation and stability and may be involved in early development of the heart. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq Dec 2010]

Gene Symbol:   ANGPT1
Gene Name:   angiopoietin 1
Aliases:   AGP1, AGPT, ANG1
RefSeq:   NC_000008.10 NT_008046.16
Ensembl:   ENSG00000154188
Entrez:   284
Chromosome Mapping:   8q23.1

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