PrimePCR™ Probe Assay: IL1RAP, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

List Price:    $263.00
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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0055299
Assay Design:   exonic
Chromosome Location:   3:190322007-190322137question
Amplicon Length:   101
Splice Variants Targeted:   ENST00000072516 ENST00000439062 ENST00000447382 ENST00000422625 ENST00000422485 ENST00000422940 ENST00000317757 ENST00000453359 ENST00000443369 ENST00000412504

Gene Information

Interleukin 1 induces synthesis of acute phase and proinflammatory proteins during infection tissue damage or stress by forming a complex at the cell membrane with an interleukin 1 receptor and an accessory protein. This gene encodes the interleukin 1 receptor accessory protein. The protein is a necessary part of the interleukin 1 receptor complex which initiates signalling events that result in the activation of interleukin 1-responsive genes. Alternative splicing of this gene results in two transcript variants encoding two different isoforms one membrane-bound and one soluble. The ratio of soluble to membrane-bound forms increases during acute-phase induction or stress. [provided by RefSeq Nov 2009]

Gene Symbol:   IL1RAP
Gene Name:   interleukin 1 receptor accessory protein
Aliases:   C3orf13, FLJ37788, IL-1RAcP, IL1R3
RefSeq:   NC_000003.11 NT_005612.16
Ensembl:   ENSG00000196083
Entrez:   3556
Chromosome Mapping:   3q28

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