PrimePCR™ Probe Assay: ANAPC10, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0057545
Assay Design:   exonic
Chromosome Location:   4:146017138-146017230question
Amplicon Length:   63
Splice Variants Targeted:   ENST00000507656 ENST00000451299 ENST00000309439 ENST00000514390 ENST00000513054 ENST00000512680 ENST00000504721 ENST00000502847

Gene Information

ANAPC10 is a core subunit of the anaphase-promoting complex (APC) or cyclosome a ubiquitin protein ligase that is essential for progression through the cell cycle. APC initiates sister chromatid separation by ubiquitinating the anaphase inhibitor securin (PTTG1; MIM 604147) and triggers exit from mitosis by ubiquitinating cyclin B (CCNB1; MIM 123836) the activating subunit of cyclin-dependent kinase-1 (CDK1; MIM 116940) (summary by Wendt et al. 2001 [PubMed 11524682]).[supplied by OMIM Feb 2011]

Gene Symbol:   ANAPC10
Gene Name:   anaphase promoting complex subunit 10
Aliases:   APC10, DKFZp564L0562, DOC1
RefSeq:   NC_000004.11 NT_016354.19
Ensembl:   ENSG00000164162
Entrez:   10393
Chromosome Mapping:   4q31

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