PrimePCR™ Probe Assay: L1CAM, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0057867
Assay Design:   exonic
Chromosome Location:   X:153129464-153129874question
Amplicon Length:   77
Splice Variants Targeted:   ENST00000370060 ENST00000370055 ENST00000370058 ENST00000361699 ENST00000543994 ENST00000370057 ENST00000538883 ENST00000361981 ENST00000599241 ENST00000598861 ENST00000593479 ENST00000597820 ENST00000594481 ENST00000595648 ENST00000601465 ENST00000598793

Gene Information

The protein encoded by this gene is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III) is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia retardation aphasia spastic paraplegia and hydrocephalus). Alternative splicing of a neuron-specific exon is thought to be functionally relevant. [provided by RefSeq Jul 2008]

Gene Symbol:   L1CAM
Gene Name:   L1 cell adhesion molecule
Aliases:   CAML1, CD171, HSAS, HSAS1, MASA, MIC5, N-CAM-L1, N-CAML1, NCAM-L1, S10, SPG1
RefSeq:   NC_000023.10 NG_009645.1 NT_167198.1
Ensembl:   ENSG00000198910
Entrez:   3897
Chromosome Mapping:   Xq28

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