PrimePCR™ Probe Assay: TNFRSF1B, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

List Price:    $263.00
Your Price:   Log In
 

Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0058012
Assay Design:   exonic
Chromosome Location:   1:12269178-12269278question
Amplicon Length:   71
Splice Variants Targeted:   ENST00000376259

Gene Information

The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins c-IAP1 and c-IAP2 which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown however c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2 which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways. [provided by RefSeq Jul 2008]

Gene Symbol:   TNFRSF1B
Gene Name:   tumor necrosis factor receptor superfamily, member 1B
Aliases:   CD120b, TBPII, TNF-R-II, TNF-R75, TNFBR, TNFR1B, TNFR2, TNFR80, p75, p75TNFR
RefSeq:   NC_000001.10 NT_021937.19
Ensembl:   ENSG00000028137
Entrez:   7133
Chromosome Mapping:   1p36.22

[ Close ]
Click here to print
[ Close ]
Click here to print
 

undefined

undefined

My PrimePCR Hot List stores your saved PrimePCR products and configurations

My PrimePCR Hot List stores your saved PrimePCR products and configurations

undefined

undefined

undefined

undefined

undefined

undefined

undefined