PrimePCR™ Probe Assay: SPP1, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCEP0058179
Assay Design:   exonic
Chromosome Location:   4:88902929-88903717question
Amplicon Length:   66
Splice Variants Targeted:   ENST00000237623 ENST00000395080 ENST00000508233 ENST00000360804

Gene Information

The protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This protein is also a cytokine that upregulates expression of interferon-gamma and interleukin-12. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq Oct 2011]

Gene Symbol:   SPP1
Gene Name:   secreted phosphoprotein 1
Aliases:   BNSP, BSPI, ETA-1, MGC110940, OPN
RefSeq:   NC_000004.11 NT_016354.19
Ensembl:   ENSG00000118785
Entrez:   6696
Chromosome Mapping:   4q22.1

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