PrimePCR™ Probe Assay: CLDN1, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

List Price:    $263.00
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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0026019
Assay Design:   Intron-spanning
Chromosome Location:   3:190030717-190039823question
Amplicon Length:   130
Splice Variants Targeted:   ENST00000295522 ENST00000545382

Gene Information

Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene a member of the claudin family is an integral membrane protein and a component of tight junction strands. Loss of function mutations result in neonatal ichthyosis-sclerosing cholangitis syndrome. [provided by RefSeq Jul 2008]

Gene Symbol:   CLDN1
Gene Name:   claudin 1
Aliases:   CLD1, ILVASC, SEMP1
RefSeq:   NC_000003.11 NG_021418.1 NT_005612.16
Ensembl:   ENSG00000163347
Entrez:   9076
Chromosome Mapping:   3q28-q29

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