PrimePCR™ Probe Assay: GZMA, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0026722
Assay Design:   Intron-spanning
Chromosome Location:   5:54398516-54401388question
Amplicon Length:   122
Splice Variants Targeted:   ENST00000274306

Gene Information

Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize bind and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface 'nonself' antigens usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here is a T cell- and natural killer cell-specific serine protease that may function as a common component necessary for lysis of target cells by cytotoxic T lymphocytes and natural killer cells. [provided by RefSeq Jul 2008]

Gene Symbol:   GZMA
Gene Name:   granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
Aliases:   CTLA3, HFSP
RefSeq:   NC_000005.9 NG_027996.1 NT_006713.15
Ensembl:   ENSG00000145649
Entrez:   3001
Chromosome Mapping:   5q11-q12

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