PrimePCR™ Probe Assay: SOD1, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

List Price:    $263.00
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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0026883
Assay Design:   Intron-spanning
Chromosome Location:   21:33036155-33039599question
Amplicon Length:   114
Splice Variants Targeted:   ENST00000270142 ENST00000389995 ENST00000535823

Gene Information

The protein encoded by this gene binds copper and zinc ions and is one of two isozymes responsible for destroying free superoxide radicals in the body. The encoded isozyme is a soluble cytoplasmic protein acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis. Rare transcript variants have been reported for this gene. [provided by RefSeq Jul 2008]

Gene Symbol:   SOD1
Gene Name:   superoxide dismutase 1, soluble
Aliases:   ALS, ALS1, IPOA, SOD, hSod1, homodimer
RefSeq:   NC_000021.8 NG_008689.1 NT_011512.11
Ensembl:   ENSG00000142168
Entrez:   6647
Chromosome Mapping:   21q22.1,21q22.11

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