PrimePCR™ Probe Assay: NRG1, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

List Price:    $263.00
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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0027789
Assay Design:   Intron-spanning
Chromosome Location:   8:32611890-32613972question
Amplicon Length:   125
Splice Variants Targeted:   ENST00000518104 ENST00000519301 ENST00000523534 ENST00000523079 ENST00000287842 ENST00000405005 ENST00000521670 ENST00000522402 ENST00000519240 ENST00000338921 ENST00000356819 ENST00000287840 ENST00000287845 ENST00000341377 ENST00000539990

Gene Information

The protein encoded by this gene was originally identified as a 44-kD glycoprotein that interacts with the NEU/ERBB2 receptor tyrosine kinase to increase its phosphorylation on tyrosine residues. This protein is a signaling protein that mediates cell-cell interactions and plays critical roles in the growth and development of multiple organ systems. It is known that an extraordinary variety of different isoforms are produced from this gene through alternative promoter usage and splicing. These isoforms are tissue-specifically expressed and differ significantly in their structure and thereby these isoforms are classified into types I II III IV V and VI. The gene dysregulation has been linked to diseases such as cancer schizophrenia and bipolar disorder (BPD). [provided by RefSeq May 2009]

Gene Symbol:   NRG1
Gene Name:   neuregulin 1
Aliases:   ARIA, GGF, GGF2, HGL, HRG, HRG1, HRGA, MST131, NDF, SMDF
RefSeq:   NC_000008.10 NT_167187.1 NG_012005.1
Ensembl:   ENSG00000157168
Entrez:   3084
Chromosome Mapping:   8p12

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