PrimePCR™ Probe Assay: MUC5B, Human

RT

Real-time PCR probe assay designed for gene expression analysis. Probe assays consist of unlabeled PCR primers and a dual labeled fluorescent probe.

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Wet Lab Validated

Assay Information

Technology:   qPCR
Assay Type:   Probe
Application:   Gene Expression
Unique Assay ID:   qHsaCIP0028135
Assay Design:   Intron-spanning
Chromosome Location:   11:1279560-1280989question
Amplicon Length:   131
Splice Variants Targeted:   ENST00000529681 ENST00000526859 ENST00000406844 ENST00000447027 ENST00000349637 ENST00000546052

Gene Information

This gene encodes a member of the mucin family of proteins which are highly glycosylated macromolecular components of mucus secretions. This family member is the major gel-forming mucin in mucus. It is a major contributor to the lubricating and viscoelastic properties of whole saliva normal lung mucus and cervical mucus. This gene has been found to be up-regulated in some human diseases including sinus mucosa of chronic rhinosinusitis (CRS) CRS with nasal polyposis chronic obstructive pulmonary disease (COPD) and H. pylori-associated gastric disease and it may be involved in the pathogenesis of these diseases. [provided by RefSeq Jul 2010]

Gene Symbol:   MUC5B
Gene Name:   mucin 5B, oligomeric mucus/gel-forming
Aliases:   MG1, MUC-5B, MUC5, MUC9
RefSeq:   NC_000011.9 NT_009237.18
Ensembl:   ENSG00000117983
Entrez:   727897
Chromosome Mapping:   11p15.5

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